Assoc. Prof. Dr. Preeyanat Vongchan, Ph.D.
Division of Transfusion Science, Department of Medical Technology
Faculty of Associated Medical Sciences
Chiang Mai University, Chiang Mai 50200, Thailand

Date of Birth April 15, 1958
Telephone    053-945080 Ext 17


Qualifications

1979    B.Sc. (Medical Technology), Faculty of Associated Medical Sciences, Chiang Mai University
1995    MSc. (Medical Technology), Faculty of Associated Medical Sciences Chiang Mai University
2002    Ph.D (Biochemistry), Faculty of Medicine, Chiang Mai University

Research experience

  1. Visiting researcher at College of Pharmacy, the University of Iowa, Iowa, USA. Scholar supported by Professor Robert J. Linhardt. July 2002 - January 2003.
  2. Visiting researcher at Rensselaer Polytechnic Institute, NY, USA. Scholar supported by Professor Robert J. Linhardt. Mar 2008 - May 2008

Research publications

  1. Vongchan P, Linhardt RJ. Characterization of a new monoclonal anti-glypican-3 antibody specific to hepatocellular carcinoma cell, HepG2, World J Hepatol, 2017; 9(7): 368-384.
  2. Tankaew P, Singh-La T, Titaram C, Punyapornwittaya V, Vongchan P, Sawada T, Sthitmatee N. Evaluation of an In-house indirect ELISA for detection of antibody against haemorrhagic septicemia in Asian elephants. J Microbiological Methods 2017; 134: 30-34.
  3. Wutti-In Y, Vongchan P, Thananchai H. Polyfunctionality of Natural Killer Cell in Healthy Donors. Walailak J Sci & Tech 2016; 13(4): 271-280.
  4. Bansiddhi P,  Vongchan P,  Satityuenyong A, Boonprasert K, Mahasawangkul S, Roongsri R, Brown JL, Thitaram C. Blood Compatibility Testing in Asian Elephants Using an Indirect Antiglobulin Technique to Improve Captive Breeding Success. Asian J. Anim. Vet. Adv 2015; 10 (12): 903-910
  5. Vongchan P. Production of a rabbit polyclonal anti-elephant IgG antibody for the elephant laboratory investigation. Chiang Mai J. Sci 2013; 40(3): 376-385.
  6. Chanungklang P, Vongchan P. Screening and identification of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University. Bull Chiang Mai Assoc Med Sci 2012; 45(2): 30-35.
  7. Vongchan P, Kothan S, Wutti-In Y, Linhardt RJ. Inhibition of Human Tumor Xenograft Growth in Nude Mice by a Novel Monoclonal Anti-HSPG Isolated from Human Liver. Anticancer research 2011; 31(12): 4067-74.
  8. Sriwichai C, Jiraudommongkol M, Wutti-In Y, Vongchan P. Production of an anti-canine globulin (polyspecific) reagent for laboratory investigation. J Small Animal Practice 2011; 52: 476-483
  9. Vongchan P, Wutti-In Y, Sajomsang W, Gonil P, Kothan S, Linhardt RJ. N,N,N-trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells. Carbohydrate Polymer 2011; 85:215-220
  10. On-Tong P, Vongchan P. Production of monoclonal antibody specific to surface antigen on hepatocellular carcinoma cell lines. Bull Chiang Mai Assoc Med Sci 2011; 44(1): 59-67
  11. Taweeapiradeechat B, Pornsilapathip J, Vongchan P. Development of FITC-conjugated monoclonal anti-human liver HSPGs, F(ab')2 for the investigation of acute myeloid leukemia by direct immunofluorescent technique. Bull Chiang Mai Assoc Med Sci. 2009; 42(2): 85-93
  12. Suwan J, Zhang Z, Li B, Vongchan P, Meepowpan P, Zhang F, Mousa SA, Mousa S, Premanode B, Kongtawelert P, Linhardt RJ. Sulfonation of papain treated chitosan and its mechanism for anticoagulant activity. Carbohydr Res 2009; 344: 1190-1196.
  13. Bunfoo J, Pornsilapathip J, Vongchan P. Production of FITC conjugated mouse monoclonal anti-heparan sulfate proteoglycans for immunologic assay. Bull Chiang Mai Assoc Med Sci. 2009; 42 (1): 50-56.
  14. Vongchan P, Nawarawong W, Linhardt RJ. Detection of anti-platelet antibodies in patients with thrombocytopenia by modified solid phase red cell adherence assay. Am J Clin Pathol 2008: 133: 455-466.
  15. Chansiw N, Pornsilapathip J, Vongchan P. Production of horseradish peroxidase conjugated anti-heparan sulfate proteoglycans antibody for immunologic assay. Bull Chiang Mai Assoc Med Sci. 2008; 41 (3): 165-174
  16. Vongchan P. Red cell antigens as functional molecules and autoimmune hemolytic anemia (AIHA). J Hematol Transf Med 2008; 18(2): 129-142
  17. Sriwichai W, Pornsilapathip J, Vongchan P. Development of detection kit for anti-platelet antibodies in patients with thrombocytopenia by modified SPRCA. Bull Chiang Mai Assoc Med Sci. 2008; 41 (1): 7-14
  18. Wutti-In Y, Pornsilapathip J, Vongchan P. Production and characterization of monoclonal antibody specific to platelet membrane molecules. Bull Chiang Mai Assoc Med Sci. 2007; 40 (3): 214-221
  19. Vongchan P, Linhardt RJ. Expression of human liver HSPGs on acute myeloid leukemia. Clin Immunol 2007; 122: 194-206
  20. Tajarungsee P, Pornsilapatip J, Vongchan P. Differentiation of myeloid leukemia by novel monoclonal antibodies specific to human liver heparan sulfate proteoglycans. J Med Tech Assoc Thailand 2006; 34(2): 1535-1541
  21. Tanvisut Y, Pornsilapatip J, Vongchan P. Production of anti-human globulins (polyspecific) reagent for blood banking use. Bull Chiang Mai Assoc Med Sci. 2006; 39 (2): 8-14
  22. Vongchan P, Linhardt RJ. Expression of human liver HSPGs on hematopoietic cancer cells. J Med Tech Assoc Thailand 2005; 33(2): 1025-1037.
  23. Vongchan P, Chantan K. Production of anti-complement antibody for development of anti-human globulin serum for blood banking use. Bull Chiang Mai Assoc Med Sci. 2005; 38 (3): 185-192.
  24. Pornprasert S, Vongchan P, et al. Production of a monoclonal antibody against a yeast secreted antigen of Penicillium marneffei. Southeast Asian J Trop Med Public Health. 2005; 36 (4): 966-969.
  25. Vongchan P, et al. Structural Characterization of Human Liver Heparan Sulfate. Biochim Biophys Acta 2005; (1721): 1-8.
  26. Vongchan P, et al. Anticoagulant Activities of the Chitosan Polysulfate Synthesized from Marine Crab Shell By Semi-heterogeneous Conditions. Science Asia. 2003; 29 (2): 115-120.
  27. Vongchan P, et al. Anticoagulant activity of a sulfated chitosan. Carbohydrate Research 2002; (337): 1239-1242.
  28. Hasslett P, Vongchan P et al. Thalidomide Stimulates T Cell Response and Interleukin 12 Production in HIV-1 Infected patients. AIDS RES HUM RETROVIRUSES. 1999; 15(13): 1169-1179.
  29. Vongchan P, Linhardt RJ. Differentiation of myeloid leukemia by novel monoclonal antibodies specific to human liver heparan sulfate proteoglycans. J Med Tech Assoc Thai. 2005; 34 (3): 1535-1541.
  30. Tanvisut Y, Vongchan P. Production of anti-human globulins (polyspecific) reagent for blood banking use. Bull Chiang Mai Assoc Med Sci. 2005; 39 (2): 8-14.
  31. Vongchan P. Case study in transfusion Medicine: Autologous blood donation. Bull Chiang Mai Assoc Med Sci. 2005; 39 (2): 185-187.
  32. Vongchan P. Case study in transfusion Medicine: Von Willebrand's disease. Bull Chiang Mai Assoc Med Sci. 2005; 39 (1): 93-94.
  33. Vongchan P. Case study in transfusion Medicine:  Complication in massive transfusion. Bull Chiang Mai Assoc Med Sci. 2005; 38 (3): 223-224.
  34. Vongchan P. Expression of human liver HSPGs on hematopoietic cancer cells. J Assoc Med Tech Thailand. 2005; 33 (2): 1065-1073.
  35. Vongchan P. Proteoglycans: Biosynthesis and structural diversity. J Med Tech Assoc Thailand. 2005; 33 (2): 1025-1037.
  36. Vongchan P. Case study in transfusion medicine: Hyperviscosity syndrome. J Med Tech Assoc Thailand.  2005; 33 (2): 1144-1148.
  37. Vongchan P. Rh Immune Globulin and clinical advantages in hemolytic disease of the newborn. Bull Chiang Mai Assoc Med Sci. 2005; 38 (2): 156
  38. Vongchan P. Production of rabbit rabbit anti-thrombocytes for the detection of anti-platelet antibodies by SPRCA technique. Bull Chiang Mai Assoc Med Sci. 2005; 38 (2): 102-110.
  39. Vongchan P. Guillain-Barre Syndrome: A Case Report. J Med Tech Assoc Thailand. 2005; 33 (1): 988-989.
  40. Vongchan P. Proteoglycans: The interesting molecules. J Med Tech Assoc Thailand. 2005; 33 (1): 900-909.
  41. Vongchan P. Special techniques in blood banking. Bull Chiang Mai Assoc Med Sci. 2005; 38 (1): 75-76.
  42. Vongchan P. Investigation of ABO discrepancies. Bull Chiang Mai Assoc Med Sci. 2004; 37 (3): 222-223.
  43. Vongchan P. Cord blood banking. Bull Chiang Mai Assoc Med Sci. 2004; 37 (2): 110-118.
  44. Vongchan P. Noninfectious transfusion reactions-3. Bull Chiang Mai Assoc Med Sci. 2004; 37 (2): 106-109.
  45. Vongchan P. Case study in transfusion medicine. Bull Chiang Mai Assoc Med Sci. 2004; 37 (1): 64-67.
  46. Vongchan P. Screening of unexpected antibodies in patients with multitransfusion by microplate technique. Bull Chiang Mai Assoc Med Sci. 2004; 36 (3): 178-185
  47. Vongchan P. Noninfectious transfusion reactions-2. Bull Chiang Mai Assoc Med Sci. 2003; 37 (1): 51-59
  48. Vongchan P. Noninfectious transfusion reactions-1. Bull Chiang Mai Assoc Med Sci. 2003; 36 (3): 208-217
  49. Vongchan P, et al. Chitosan polysulfate synthesized from marine crab shell inhibited PPD stimulated human PBMC proliferation. Chiang Mai Medical Bulletin. 2001; 41 (4): 179-188.
  50. Vongchan P. Blood safety in blood banking. Bull Chiang Mai Assoc Med Sci. 2002; 35 (3): 202-205.
  51. Fongmoon D, Vongchan P Detection of platelet antibodies by platelet Suspension immunofluorescent technique. Thai J Hematol Tansf Med. 2001; 11 (2): 73-83.
  52. Vongchan P. Ku protein. Bull Chiang Mai Assoc Med Sci. 2001; 34 (1): 47-50.
  53. Vongchan P, et al. Preparation of Polyclonal and Monoclonal antibodies against HIV p24 antigen and development of Immunoassay for HIV p24 antigen. Bull Chiang Mai Assoc Med Sci. 1999; 38: 83-83.




Administrative status

  •     Associate Dean (Administrative  and Academic Services)
  •     Head of the Division of Transfusion Science, Department of Medical Technology, Faculty of Associated Medical Science
  •     Editor of Journal of Associated Medical Sciences (JAMS)


Research Primary Investigator

  1. Identification and characterization of a new monoclonal antibody specific to heparan sulfate proteoglycans on hepatocellular carcinoma cells for the development of diagnostic tumor marker and tumor-targeted immunotherapy 2016-2017 (NRCT)
  2. Identification and characterization of glypican-3 co-partner on HepG2 cell line for a development of the new therapeutic target of hepatocellular carcinoma 2015-2016 (NRCT)
  3. In vivo study of hepatocellular carcinoma targeted monoclonal antibody conjugated chitosan based polymeric micelle in the inhibition of cancer growth 2014-2015 (NRCT)
  4. Preparation of monoclonal antibody conjugated chitosan based polymeric micelle for targeted hepatocellular carcinoma drug delivery system 2013-2014 (NRCT)
  5. Biochemical characterization of a new heparan sulfate proteoglycan on granulocytes and the study of its role in granulocyte differentiation. 2012-2013, (NRCT)
  6. Characterization of high potential panel monoclonal antibodies specific to human liver heparan sulfate protoglycans for the development of hepatocellular carcinoma investigation kit. 2010-2011, (NRCT)
  7. Preparation of water-soluble chitosan derivatives delivered anti-HSPG and study of its inhibition effect on metastasis and implantation of cancer cells in animal model. 2009-2010, (NRCT)
  8. Characterization of monoclonal antibodies specific to human liver heparan sulfate proteoglycans: The development of reagent kit for diagnosis of liver damage and the study of inhibition effects on tumor implantation and metastasis. 2008-2009 (NRCT)
  9. Expression of liver HSPGs on cancer cells and the applications use of MAbs specific to liver HSPGs in the inhibition effect of cancer cell growth and metastasis. 2007-2009, (TRF)
  10. Preparation of water-soluble chitosan derivatives delivered anti-HSPG. 2007-2008, (NRCT)
  11. Characterization of a monoclonal antibody specific to human liver HSPGs: The development of reagent kit for diagnosis of liver damage and the study of inhibition effects on tumor implantation and metastasis. 2006-2007, (NRCT)
  12. Development of FITC-conjugated anti-human liver HSPGs, F(ab)'2 for the investigation of acute myeloid leukemia by direct immunofluorescent technique. 2008, (IRPUS-TRF)
  13. Development of sandwich ELISA for the detection of shading HSPG in sera of patients with liver diseases using home-made biotinylated anti-human liver HSPG. 2008,  (IRPUS-TRF)
  14. Production of rabbit anti-canine immunoglobulins for canine blood crossmatching. 2008, (IRPUS-TRF)
  15. Characterization of monoclonal antibodies specific to human liver heparan sulfate proteoglycans: The development of reagent kit for diagnosis of liver damage and study of inhibition effects on tumor implantation and metastasis. 2006-2008, (NCRT)
  16. Production of FITC-conjugated mouse anti-human liver HSPGs for immunologic assay. 2007, (IRPUS-TRF)
  17. Production of HRP- conjugated mouse anti-human liver HSPGs for immunologic assay. 2007, (IRPUS-TRF)
  18. Production and characterization of a monoclonal antibody specific to human liver HSPGs as a co-marker for diagnosis of myeloid leukemia. 2006, (IRPUS-TRF)
  19. Production and characterization of a monoclonal antibody specific to human platelet membrane molecules. 2006, (IRPUS-TRF)
  20. Detection of anti-platelet antibodies in patients with thrombocytopenia by modified SPRCA technique. 2006, (IRPUS-TRF)
  21. Differentiation of myeloid leukemia using monoclonal antibody specific to human liver HSPGs. 2005, (IRPUS-TRF)
  22. Production of anti-human globulin (polyspecific) reagent for blood banking use. 2005, IRPUS-TRF
  23. Production of polyclonal rabbit anti-human complement for the preparation of anti-human globulin reagent. 2004, (IRPUS-TRF)
  24. Production of polyclonal rabbit anti-thrombocytes for the detection of anti-platelet antibodies by SPRCA technique. 2004, MT-CMU
  25. Production of  monoclonal antibodies specific to human liver HSPGs. 2003-2004, TRF
  26. Production of monoclonal antibodies specific to human platelet gpIIbIIIa. 1996, CMU

Book editor

  • Preeyanat Vongchan 2016: Proteoglycans: Biochemistry and clinical applications
  • Preeyanat Vongchan 2016: Technical Manuals in Transfusion Sciences.
  • Preeyanat Vongchan 2015: Transfusion Sciences Book 2
  • Preeyanat Vongchan 2014: Transfusion Sciences Book 1
  • Preeyanat Vongchan 2005: Reagents and Solution for Biomedical Laboratory
  • Preeyanat Vongchan 2005: Technical Manuals in Blood Banking.

Field of interest

Blood banking    : Platelet immunology and clinical laboratory investigation, Immunohematology and Blood banking
Immunology        : Antibody production
Biochemistry      : Heparan sulfate proteoglycans isolated from human liver: Distribution and characteristics, Production of monoclonal antibodies specific to HSPG and clinical application use.
Thai Medicinal Formula and anti-cancer activity

AMS
MT
CMU
RT